diff --git a/dd-java-agent/agent-bootstrap/src/main/java/datadog/trace/bootstrap/instrumentation/jdbc/JDBCConnectionUrlParser.java b/dd-java-agent/agent-bootstrap/src/main/java/datadog/trace/bootstrap/instrumentation/jdbc/JDBCConnectionUrlParser.java
index 34b1c7407d2..f9352c13eaa 100644
--- a/dd-java-agent/agent-bootstrap/src/main/java/datadog/trace/bootstrap/instrumentation/jdbc/JDBCConnectionUrlParser.java
+++ b/dd-java-agent/agent-bootstrap/src/main/java/datadog/trace/bootstrap/instrumentation/jdbc/JDBCConnectionUrlParser.java
@@ -781,6 +781,20 @@ DBInfo.Builder doParse(String jdbcUrl, DBInfo.Builder builder) {
       }
       return GENERIC_URL_LIKE.doParse(url, builder);
     }
+  },
+
+  IRIS("iris") {
+    @Override
+    DBInfo.Builder doParse(String jdbcUrl, DBInfo.Builder builder) {
+      String url = jdbcUrl;
+      int firstSlash = url.indexOf('/', "jdbc://iris:/".length());
+      int nextSlash = url.indexOf('/', firstSlash + 1);
+      if (nextSlash > firstSlash) {
+        // strip the options and preserve only the url like part
+        url = url.substring(0, nextSlash);
+      }
+      return GENERIC_URL_LIKE.doParse(url, builder);
+    }
   };
 
   private static final Map<String, JDBCConnectionUrlParser> typeParsers = new HashMap<>();
diff --git a/dd-java-agent/instrumentation/jdbc/src/main/java/datadog/trace/instrumentation/jdbc/DefaultConnectionInstrumentation.java b/dd-java-agent/instrumentation/jdbc/src/main/java/datadog/trace/instrumentation/jdbc/DefaultConnectionInstrumentation.java
index 16ff9c654b4..525fde5d7f9 100644
--- a/dd-java-agent/instrumentation/jdbc/src/main/java/datadog/trace/instrumentation/jdbc/DefaultConnectionInstrumentation.java
+++ b/dd-java-agent/instrumentation/jdbc/src/main/java/datadog/trace/instrumentation/jdbc/DefaultConnectionInstrumentation.java
@@ -41,6 +41,8 @@ public class DefaultConnectionInstrumentation extends AbstractConnectionInstrume
     "com.sap.db.jdbc.ConnectionSapDB",
     // IBM Informix
     "com.informix.jdbc.IfmxConnection",
+    // Intersystems IRIS
+    "com.intersystems.jdbc.IRISConnection",
     // for testing purposes
     "test.TestConnection"
   };
diff --git a/dd-java-agent/instrumentation/jdbc/src/main/java/datadog/trace/instrumentation/jdbc/PreparedStatementInstrumentation.java b/dd-java-agent/instrumentation/jdbc/src/main/java/datadog/trace/instrumentation/jdbc/PreparedStatementInstrumentation.java
index 38d818b2676..86d94fa3255 100644
--- a/dd-java-agent/instrumentation/jdbc/src/main/java/datadog/trace/instrumentation/jdbc/PreparedStatementInstrumentation.java
+++ b/dd-java-agent/instrumentation/jdbc/src/main/java/datadog/trace/instrumentation/jdbc/PreparedStatementInstrumentation.java
@@ -117,6 +117,9 @@ public final class PreparedStatementInstrumentation extends AbstractPreparedStat
     "software.aws.rds.jdbc.mysql.shading.com.mysql.cj.JdbcCallableStatement",
     // IBM Informix
     "com.informix.jdbc.IfxPreparedStatement",
+    // Intersystems IRIS
+    "com.intersystems.jdbc.IRISPreparedStatement",
+    "com.intersystems.jdbc.IRISCallableStatement",
     // for testing purposes
     "test.TestPreparedStatement"
   };
diff --git a/dd-java-agent/instrumentation/jdbc/src/test/groovy/JDBCConnectionUrlParserTest.groovy b/dd-java-agent/instrumentation/jdbc/src/test/groovy/JDBCConnectionUrlParserTest.groovy
index a3d1a73a211..fe12885b99c 100644
--- a/dd-java-agent/instrumentation/jdbc/src/test/groovy/JDBCConnectionUrlParserTest.groovy
+++ b/dd-java-agent/instrumentation/jdbc/src/test/groovy/JDBCConnectionUrlParserTest.groovy
@@ -200,6 +200,10 @@ class JDBCConnectionUrlParserTest extends AgentTestRunner {
 
     // redshift
     "jdbc:redshift://redshift-cluster-1.c7arcolffyvk.us-east-2.redshift.amazonaws.com:5439/dev"                                                                                                                                                 | null     | "redshift"   | null          | null          | "redshift-cluster-1.c7arcolffyvk.us-east-2.redshift.amazonaws.com"  | 5439  | "redshift-cluster-1"               | "dev"
+    // Intersys IRIS
+    "jdbc:IRIS://dbhostname:1972/namespace"                                                                                                                                                                                                     | null     | "iris"       | null          | null          | "dbhostname"  | 1972  | null               | "namespace"
+    "jdbc:IRIS://dbhostname:1972/namespace/+myjdbc.log"                                                                                                                                                                                                     | null     | "iris"       | null          | null          | "dbhostname"  | 1972  | null               | "namespace"
+    "jdbc:IRIS://dbhostname:1972/namespace/::false"                                                                                                                                                                                             | null     | "iris"       | null          | null          | "dbhostname"  | 1972  | null               | "namespace"
 
     expected = new DBInfo.Builder().type(type).subtype(subtype).user(user).instance(instance).db(db).host(host).port(port).build()
   }