diff --git a/src/components/Tooltip/Tooltip.tsx b/src/components/Tooltip/Tooltip.tsx
index 178b9d419..12c5585eb 100644
--- a/src/components/Tooltip/Tooltip.tsx
+++ b/src/components/Tooltip/Tooltip.tsx
@@ -1,12 +1,13 @@
 import { PropsWithChildren } from 'react';
 import * as React from 'react';
-import TetherComponent from 'react-tether';
-import styled, { createGlobalStyle, keyframes } from 'styled-components';
-import { Colors, Elevation, MediaQueries } from '../../essentials';
+import styled, { keyframes } from 'styled-components';
+import { usePopper } from 'react-popper';
+import { Placement } from '@popperjs/core/lib/enums';
+import { variant } from 'styled-system';
+import { Colors, MediaQueries } from '../../essentials';
 import { get } from '../../utils/themeGet';
 import { Text } from '../Text/Text';
-import { TooltipPlacement } from './TooltipPlacement';
-import { getAttachmentFromPlacement } from './util/getAttachmentFromPlacement';
+import { mapPlacementWithDeprecationWarning, TooltipPlacement } from './TooltipPlacement';
 
 const fadeAnimation = keyframes`
     from {
@@ -18,7 +19,73 @@ const fadeAnimation = keyframes`
     }
 `;
 
-const TooltipBody = styled.div<Pick<TooltipProps, 'inverted'>>`
+const arrowPlacementStyles = variant({
+    variants: {
+        bottom: {
+            right: 'calc(50% - 0.25rem)'
+        },
+        'bottom-end': {
+            right: '0.3rem'
+        },
+        'top-start': {
+            bottom: '-0.5rem',
+            transform: 'rotate(-180deg)'
+        },
+        top: {
+            bottom: '-0.5rem',
+            transform: 'rotate(-180deg)',
+            right: 'calc(50% - 0.25rem)'
+        },
+        'top-end': {
+            bottom: '-0.5rem',
+            transform: 'rotate(-180deg)',
+            right: '0.3rem'
+        },
+        left: {
+            top: 'calc(50% - 0.25rem)',
+            left: 'auto',
+            right: '-0.5rem',
+            transform: 'rotate(90deg)'
+        },
+        'left-end': {
+            bottom: '0.5rem',
+            left: 'auto',
+            right: '-0.5rem',
+            transform: 'rotate(90deg)'
+        },
+        'left-start': {
+            top: '0.5rem',
+            left: 'auto',
+            right: '-0.5rem',
+            transform: 'rotate(90deg)'
+        },
+        right: {
+            top: 'calc(50% - 0.25rem)',
+            left: '-0.25rem',
+            right: 'auto',
+            transform: 'rotate(-90deg)'
+        },
+        'right-end': {
+            bottom: '0.5rem',
+            left: '-0.25rem',
+            right: 'auto',
+            transform: 'rotate(-90deg)'
+        },
+        'right-start': {
+            top: '0.5rem',
+            left: '-0.25rem',
+            right: 'auto',
+            transform: 'rotate(-90deg)'
+        }
+    }
+});
+
+interface TooltipBodyProps {
+    inverted?: boolean;
+    variant: string;
+}
+
+const TooltipBody = styled.div<TooltipBodyProps>`
     position: relative;
     background-color: ${p => (p.inverted ? Colors.AUTHENTIC_BLUE_50 : Colors.AUTHENTIC_BLUE_900)};
     padding: 0.25rem 0.5rem;
@@ -45,83 +112,8 @@ const TooltipBody = styled.div<Pick<TooltipProps, 'inverted'>>`
         border: 0.25rem solid rgba(0, 0, 0, 0);
         border-bottom-color: ${p => (p.inverted ? Colors.AUTHENTIC_BLUE_50 : Colors.AUTHENTIC_BLUE_900)};
         margin-left: -0.25rem;
-    }
-`;
-
-const GlobalTetherStyles = createGlobalStyle`
-    body > .tether-element {
-        z-index: ${Elevation.TOOLTIP};
-    }
-
-    .tether-target-attached-bottom {
-        & > ${TooltipBody} {
-            margin-top: 0.5rem;
-
-            &::after {
-                top: -0.5rem;
-            }
-        }
-    }
-
-    .tether-target-attached-top {
-        & > ${TooltipBody} {
-            top: -0.5rem;
-
-            &::after {
-                bottom: -0.5rem;
-                transform: rotate(-180deg);
-            }
-        }
-    }
-    
-    .tether-target-attached-center {
-        & > ${TooltipBody} {
-            &::after {
-                left: 50%;
-            }
-        }
-    }
-    
-    .tether-target-attached-left {
-        & > ${TooltipBody} {
-            &::after {
-                left: 1rem;
-            }
-        }
-    }
-
-    .tether-target-attached-right {
-        & > ${TooltipBody} {
-            &::after {
-                right: 1rem;
-            }
-        }
-    }
-
-    .tether-target-attached-middle.tether-target-attached-right {
-        & > ${TooltipBody} {
-            margin-left: 0.5rem;
-
-            &::after {
-                top: calc(50% - 0.25rem);
-                left: -0.25rem;
-                right: auto;
-                transform: rotate(-90deg);
-            }
-        }
-    }
-
-    .tether-target-attached-middle.tether-target-attached-left {
-        & > ${TooltipBody} {
-           left: -0.5rem;
 
-            &::after {
-                top: calc(50% - 0.25rem);
-                left: auto;
-                right: -0.5rem;
-                transform: rotate(90deg);
-            }
-        }
+        ${arrowPlacementStyles}
     }
 `;
 
@@ -131,9 +123,9 @@ interface TooltipProps {
      */
     content: React.ReactNode;
     /**
-     * Set the position of where the tooltip is attached to the target, defaults to "top-center"
+     * Set the position of where the tooltip is attached to the target, defaults to "top"
      */
-    placement?: TooltipPlacement;
+    placement?: TooltipPlacement | Placement;
     /**
      * Adjust the component for display on dark backgrounds
      */
@@ -147,11 +139,37 @@ interface TooltipProps {
 const Tooltip: React.FC<TooltipProps> = ({
     content,
     children,
-    placement = 'top-center',
+    placement = 'top',
     alwaysVisible = false,
     inverted = false
 }: PropsWithChildren<TooltipProps>) => {
     const [isVisible, setIsVisible] = React.useState(alwaysVisible);
+    /**
+     * triggerReference and contentReference are used with the Popper library in order to get the tooltip styles and attributes
+     */
+    const [triggerReference, setTriggerReference] = React.useState(undefined);
+    const [contentReference, setContentReference] = React.useState(undefined);
+
+
+    /**
+     * Map the older placement values to Popper placement  as we need to get the correct placement for the tooltip from the Popper library
+     * without introduce any breaking changes to the Tooltip component.
+     * TODO: Remove in the next major release.
+     */
+    const mappedPlacement = mapPlacementWithDeprecationWarning(placement);
+
+    const { styles, attributes } = usePopper(triggerReference, contentReference, {
+        placement: mappedPlacement,
+        modifiers: [
+            {
+                name: 'offset',
+                enabled: true,
+                options: {
+                    offset: [0, 5]
+                }
+            }
+        ]
+    });
 
     let dynamicContent = content;
 
@@ -171,30 +189,22 @@ const Tooltip: React.FC<TooltipProps> = ({
 
     return (
         <>
-            <TetherComponent
-                {...getAttachmentFromPlacement(placement)}
-                constraints={[
-                    {
-                        to: 'window',
-                        attachment: 'together'
-                    }
-                ]}
-                renderTarget={ref =>
-                    React.cloneElement(children as React.ReactElement, {
-                        onMouseOver: () => handleVisibilityChange(true),
-                        onMouseOut: () => handleVisibilityChange(false),
-                        ref
-                    })
-                }
-                renderElement={(ref: React.RefObject<HTMLDivElement>) =>
-                    isVisible && (
-                        <TooltipBody ref={ref} inverted={inverted}>
-                            {dynamicContent}
-                        </TooltipBody>
-                    )
-                }
-            />
-            <GlobalTetherStyles />
+            {React.cloneElement(children as React.ReactElement, {
+                onMouseOver: () => handleVisibilityChange(true),
+                onMouseOut: () => handleVisibilityChange(false),
+                ref: setTriggerReference
+            })}
+            {content && isVisible && (
+                <TooltipBody
+                    ref={setContentReference}
+                    inverted={inverted}
+                    style={{ ...styles.popper }}
+                    variant={attributes.popper?.['data-popper-placement']}
+                    {...attributes.popper}
+                >
+                    {dynamicContent}
+                </TooltipBody>
+            )}
         </>
     );
 };
diff --git a/src/components/Tooltip/TooltipPlacement.ts b/src/components/Tooltip/TooltipPlacement.ts
index 949af115c..39a67fcc4 100644
--- a/src/components/Tooltip/TooltipPlacement.ts
+++ b/src/components/Tooltip/TooltipPlacement.ts
@@ -1,3 +1,6 @@
+import { Placement } from '@popperjs/core';
+import { deprecatedProperty } from '../../utils/deprecatedProperty';
+
 export type TooltipPlacement =
     | 'bottom-left'
     | 'bottom-center'
@@ -7,3 +10,21 @@ export type TooltipPlacement =
     | 'top-right'
     | 'center-left'
     | 'center-right';
+
+const TOOLTIP_TO_POPPER_PLACEMENT_MAP: { [key in TooltipPlacement]: Placement } = {
+    'bottom-left': 'bottom-start',
+    'bottom-center': 'bottom',
+    'bottom-right': 'bottom-end',
+    'top-left': 'top-start',
+    'top-center': 'top',
+    'top-right': 'top-end',
+    'center-left': 'left',
+    'center-right': 'right'
+};
+
+export const mapPlacementWithDeprecationWarning = (placement: TooltipPlacement | Placement): Placement => {
+    const mappedPlacement = TOOLTIP_TO_POPPER_PLACEMENT_MAP[placement as TooltipPlacement];
+    if (mappedPlacement)
+        deprecatedProperty('Tooltip', placement, `Value '${placement}' for placement`, mappedPlacement);
+    return mappedPlacement ?? (placement as Placement);
+};
diff --git a/src/components/Tooltip/docs/Tooltip.mdx b/src/components/Tooltip/docs/Tooltip.mdx
index 019c2a447..c0abb16cb 100644
--- a/src/components/Tooltip/docs/Tooltip.mdx
+++ b/src/components/Tooltip/docs/Tooltip.mdx
@@ -29,6 +29,10 @@ This component provides informative text to an UI element.
 
 Use the tooltip for user on-boarding, guiding information about a new feature, detailed interactive workflows or for a contextual help (eg. over a button).
 
+## Properties
+
+<TooltipPropsTable />
+
 ## Appearance
 
 -   The font size is 12px and font weight is regular.
@@ -49,7 +53,7 @@ Use the tooltip for user on-boarding, guiding information about a new feature, d
 It is possible to adjust the position of the tooltip connection to the target with the `placement` prop. Below is a list
 of possible options which are represented in the square next to it. It is important to keep in mind that the tooltip
 will be moved to a different position if it cannot be shown on the desired side due to screen sizes. Read more about the
-Tether library [here](http://tether.io).
+Popper library [here](https://popper.js.org/).
 
 <TooltipPlacementExample />
 
diff --git a/src/components/Tooltip/docs/TooltipPlacementExample.tsx b/src/components/Tooltip/docs/TooltipPlacementExample.tsx
index 6116a28b8..c8b6d8fa5 100644
--- a/src/components/Tooltip/docs/TooltipPlacementExample.tsx
+++ b/src/components/Tooltip/docs/TooltipPlacementExample.tsx
@@ -1,9 +1,9 @@
 import { FC } from 'react';
 import * as React from 'react';
 import styled from 'styled-components';
+import { Placement } from '@popperjs/core/lib/enums';
 import { RadioButton, Tooltip } from '../..';
 import { Colors, MediaQueries } from '../../../essentials';
-import { TooltipPlacement } from '../TooltipPlacement';
 
 const TargetSquare = styled.div`
     background: ${Colors.BUMPY_MAGENTA_50};
@@ -35,17 +35,24 @@ const ExampleContainer = styled.div`
 `;
 
 const TooltipPlacementExample: FC = () => {
-    const [placement, setPlacement] = React.useState<TooltipPlacement>('top-center');
+    const [placement, setPlacement] = React.useState<Placement>('top');
 
-    const availablePlacements: TooltipPlacement[] = [
-        'top-left',
-        'top-center',
-        'top-right',
-        'bottom-left',
-        'bottom-center',
-        'bottom-right',
-        'center-left',
-        'center-right'
+    const availablePlacements: Placement[] = [
+        'top-start',
+        'top-end',
+        'bottom-start',
+        'bottom-end',
+        'right-start',
+        'right-end',
+        'left-start',
+        'left-end',
+        'top',
+        'bottom',
+        'right',
+        'left',
+        'auto',
+        'auto-start',
+        'auto-end'
     ];
 
     return (
diff --git a/src/components/Tooltip/docs/TooltipPropsTable.tsx b/src/components/Tooltip/docs/TooltipPropsTable.tsx
index 6c7198c74..6d54205b4 100644
--- a/src/components/Tooltip/docs/TooltipPropsTable.tsx
+++ b/src/components/Tooltip/docs/TooltipPropsTable.tsx
@@ -1,29 +1,32 @@
-import React, { FC } from 'react';
-
+import * as React from 'react';
 import { PropsTable } from '../../../docs/PropsTable';
 
-export const TooltipPropsTable: FC = () => {
+export const TooltipPropsTable = () => {
     const props = [
         {
             name: 'content',
-            type: 'React.ReactNode',
-            description: 'The content that will be shown inside of the tooltip body.'
+            type: 'React.ReactNode | string',
+            description: 'The content that will be shown inside of the tooltip body',
+            defaultValue: '-'
         },
         {
             name: 'placement',
-            type: 'TooltipPlacement (see the Placement section below for values)',
-            description: 'Set the position of where the tooltip is attached to the target.',
-            defaultValue: 'top-center'
+            type:
+                '"top-start" | "top-end" | "bottom-start" | "bottom-end" | "right-start" | "right-end" | "left-start" | "left-end" | "top" | "bottom" | "right" | "left" | "auto" | "auto-start" | "auto-end"',
+            description: 'Set the position of where the tooltip is attached to the target',
+            defaultValue: 'top'
         },
         {
             name: 'inverted',
             type: 'boolean',
-            description: 'Adjust the component for display on dark backgrounds.'
+            description: 'Adjust color for display on a dark background',
+            defaultValue: 'false'
         },
         {
             name: 'alwaysVisible',
             type: 'boolean',
-            description: 'Force the tooltip to always be visible, regardless of user interaction.'
+            description: 'Force the tooltip to always be visible, regardless of user interaction',
+            defaultValue: 'false'
         }
     ];
     return <PropsTable props={props} />;
diff --git a/src/components/Tooltip/util/getAttachmentFromPlacement.ts b/src/components/Tooltip/util/getAttachmentFromPlacement.ts
deleted file mode 100644
index 22e194b3c..000000000
--- a/src/components/Tooltip/util/getAttachmentFromPlacement.ts
+++ /dev/null
@@ -1,55 +0,0 @@
-import { TooltipPlacement } from '../TooltipPlacement';
-
-// we need to convert the users `placement` prop to react-tether `attachment` and `targetAttachment`
-export const getAttachmentFromPlacement = (
-    placement: TooltipPlacement
-): { attachment: string; targetAttachment: string } => {
-    switch (placement) {
-        case 'bottom-left':
-            return {
-                attachment: 'top left',
-                targetAttachment: 'bottom left'
-            };
-
-        case 'bottom-center':
-            return {
-                attachment: 'top center',
-                targetAttachment: 'bottom center'
-            };
-        case 'bottom-right':
-            return {
-                attachment: 'top right',
-                targetAttachment: 'bottom right'
-            };
-        case 'top-left':
-            return {
-                attachment: 'bottom left',
-                targetAttachment: 'top left'
-            };
-        case 'top-center':
-            return {
-                attachment: 'bottom center',
-                targetAttachment: 'top center'
-            };
-        case 'top-right':
-            return {
-                attachment: 'bottom right',
-                targetAttachment: 'top right'
-            };
-        case 'center-left':
-            return {
-                attachment: 'middle right',
-                targetAttachment: 'middle left'
-            };
-        case 'center-right':
-            return {
-                attachment: 'middle left',
-                targetAttachment: 'middle right'
-            };
-        default:
-            return {
-                attachment: 'bottom center',
-                targetAttachment: 'top center'
-            };
-    }
-};