diff --git a/packages/replay/src/coreHandlers/handleNetworkBreadcrumbs.ts b/packages/replay/src/coreHandlers/handleNetworkBreadcrumbs.ts
index 59324031e336..20fa00a633eb 100644
--- a/packages/replay/src/coreHandlers/handleNetworkBreadcrumbs.ts
+++ b/packages/replay/src/coreHandlers/handleNetworkBreadcrumbs.ts
@@ -31,13 +31,19 @@ export function handleNetworkBreadcrumbs(replay: ReplayContainer): void {
   try {
     const textEncoder = new TextEncoder();
 
-    const { networkDetailAllowUrls, networkCaptureBodies, networkRequestHeaders, networkResponseHeaders } =
-      replay.getOptions();
+    const {
+      networkDetailAllowUrls,
+      networkDetailDenyUrls,
+      networkCaptureBodies,
+      networkRequestHeaders,
+      networkResponseHeaders,
+    } = replay.getOptions();
 
     const options: ExtendedNetworkBreadcrumbsOptions = {
       replay,
       textEncoder,
       networkDetailAllowUrls,
+      networkDetailDenyUrls,
       networkCaptureBodies,
       networkRequestHeaders,
       networkResponseHeaders,
diff --git a/packages/replay/src/coreHandlers/util/fetchUtils.ts b/packages/replay/src/coreHandlers/util/fetchUtils.ts
index 9411332d0197..491fe727b1b8 100644
--- a/packages/replay/src/coreHandlers/util/fetchUtils.ts
+++ b/packages/replay/src/coreHandlers/util/fetchUtils.ts
@@ -85,7 +85,8 @@ async function _prepareFetchData(
     response_body_size: responseBodySize,
   } = breadcrumb.data;
 
-  const captureDetails = urlMatches(url, options.networkDetailAllowUrls);
+  const captureDetails =
+    urlMatches(url, options.networkDetailAllowUrls) && !urlMatches(url, options.networkDetailDenyUrls);
 
   const request = captureDetails
     ? _getRequestInfo(options, hint.input, requestBodySize)
diff --git a/packages/replay/src/coreHandlers/util/xhrUtils.ts b/packages/replay/src/coreHandlers/util/xhrUtils.ts
index dfb1ccaf3ffc..638af2cbdb5c 100644
--- a/packages/replay/src/coreHandlers/util/xhrUtils.ts
+++ b/packages/replay/src/coreHandlers/util/xhrUtils.ts
@@ -78,7 +78,7 @@ function _prepareXhrData(
     return null;
   }
 
-  if (!urlMatches(url, options.networkDetailAllowUrls)) {
+  if (!urlMatches(url, options.networkDetailAllowUrls) || urlMatches(url, options.networkDetailDenyUrls)) {
     const request = buildSkippedNetworkRequestOrResponse(requestBodySize);
     const response = buildSkippedNetworkRequestOrResponse(responseBodySize);
     return {
diff --git a/packages/replay/src/integration.ts b/packages/replay/src/integration.ts
index 2baf117b5c38..2e795829894b 100644
--- a/packages/replay/src/integration.ts
+++ b/packages/replay/src/integration.ts
@@ -67,6 +67,7 @@ export class Replay implements Integration {
     slowClickIgnoreSelectors = [],
 
     networkDetailAllowUrls = [],
+    networkDetailDenyUrls = [],
     networkCaptureBodies = true,
     networkRequestHeaders = [],
     networkResponseHeaders = [],
@@ -138,6 +139,7 @@ export class Replay implements Integration {
       slowClickTimeout,
       slowClickIgnoreSelectors,
       networkDetailAllowUrls,
+      networkDetailDenyUrls,
       networkCaptureBodies,
       networkRequestHeaders: _getMergedNetworkHeaders(networkRequestHeaders),
       networkResponseHeaders: _getMergedNetworkHeaders(networkResponseHeaders),
diff --git a/packages/replay/src/types/replay.ts b/packages/replay/src/types/replay.ts
index e2cfddd0f525..494d9408f292 100644
--- a/packages/replay/src/types/replay.ts
+++ b/packages/replay/src/types/replay.ts
@@ -70,23 +70,32 @@ export interface ReplayNetworkOptions {
    */
   networkDetailAllowUrls: (string | RegExp)[];
 
+  /**
+   * Deny request/response details for XHR/Fetch requests that match the given URLs.
+   * The URLs can be strings or regular expressions.
+   * When provided a string, we will deny any URL that contains the given string.
+   * You can use a Regex to handle exact matches or more complex matching.
+   * URLs matching these patterns will not have bodies & additional headers captured.
+   */
+  networkDetailDenyUrls: (string | RegExp)[];
+
   /**
    * If request & response bodies should be captured.
-   * Only applies to URLs matched by `networkDetailAllowUrls`.
+   * Only applies to URLs matched by `networkDetailAllowUrls` and not matched by `networkDetailDenyUrls`.
    * Defaults to true.
    */
   networkCaptureBodies: boolean;
 
   /**
    * Capture the following request headers, in addition to the default ones.
-   * Only applies to URLs matched by `networkDetailAllowUrls`.
+   * Only applies to URLs matched by `networkDetailAllowUrls` and not matched by `networkDetailDenyUrls`.
    * Any headers defined here will be captured in addition to the default headers.
    */
   networkRequestHeaders: string[];
 
   /**
    * Capture the following response headers, in addition to the default ones.
-   * Only applies to URLs matched by `networkDetailAllowUrls`.
+   * Only applies to URLs matched by `networkDetailAllowUrls` and not matched by `networkDetailDenyUrls`.
    * Any headers defined here will be captured in addition to the default headers.
    */
   networkResponseHeaders: string[];
diff --git a/packages/replay/test/unit/coreHandlers/handleNetworkBreadcrumbs.test.ts b/packages/replay/test/unit/coreHandlers/handleNetworkBreadcrumbs.test.ts
index 825c6e4eb452..c0ad9ef59b49 100644
--- a/packages/replay/test/unit/coreHandlers/handleNetworkBreadcrumbs.test.ts
+++ b/packages/replay/test/unit/coreHandlers/handleNetworkBreadcrumbs.test.ts
@@ -63,6 +63,7 @@ describe('Unit | coreHandlers | handleNetworkBreadcrumbs', () => {
         textEncoder: new TextEncoder(),
         replay: setupReplayContainer(),
         networkDetailAllowUrls: ['https://example.com'],
+        networkDetailDenyUrls: ['http://localhost:8080'],
         networkCaptureBodies: false,
         networkRequestHeaders: ['content-type', 'accept', 'x-custom-header'],
         networkResponseHeaders: ['content-type', 'accept', 'x-custom-header'],
@@ -1382,5 +1383,166 @@ other-header: test`;
         ]);
       });
     });
+
+    describe.each([
+      ['exact string match', 'https://example.com/foo'],
+      ['partial string match', 'https://example.com/bar/what'],
+      ['exact regex match', 'http://example.com/exact'],
+      ['partial regex match', 'http://example.com/partial/string'],
+    ])('matching URL %s', (_label, url) => {
+      it('correctly deny URL for fetch request', async () => {
+        options.networkDetailDenyUrls = [
+          'https://example.com/foo',
+          'com/bar',
+          /^http:\/\/example.com\/exact$/,
+          /^http:\/\/example.com\/partial/,
+        ];
+
+        const breadcrumb: Breadcrumb = {
+          category: 'fetch',
+          data: {
+            method: 'GET',
+            url,
+            status_code: 200,
+          },
+        };
+
+        const mockResponse = getMockResponse('13', 'test response');
+
+        const hint: FetchBreadcrumbHint = {
+          input: ['GET', { body: 'test input' }],
+          response: mockResponse,
+          startTimestamp: BASE_TIMESTAMP + 1000,
+          endTimestamp: BASE_TIMESTAMP + 2000,
+        };
+        beforeAddNetworkBreadcrumb(options, breadcrumb, hint);
+
+        expect(breadcrumb).toEqual({
+          category: 'fetch',
+          data: {
+            method: 'GET',
+            request_body_size: 10,
+            response_body_size: 13,
+            status_code: 200,
+            url,
+          },
+        });
+
+        await waitForReplayEventBuffer();
+
+        expect((options.replay.eventBuffer as EventBufferArray).events).toEqual([
+          {
+            data: {
+              payload: {
+                data: {
+                  method: 'GET',
+                  request: {
+                    _meta: {
+                      warnings: ['URL_SKIPPED'],
+                    },
+                    headers: {},
+                    size: 10,
+                  },
+                  response: {
+                    _meta: {
+                      warnings: ['URL_SKIPPED'],
+                    },
+                    headers: {},
+                    size: 13,
+                  },
+                  statusCode: 200,
+                },
+                description: url,
+                endTimestamp: (BASE_TIMESTAMP + 2000) / 1000,
+                op: 'resource.fetch',
+                startTimestamp: (BASE_TIMESTAMP + 1000) / 1000,
+              },
+              tag: 'performanceSpan',
+            },
+            timestamp: (BASE_TIMESTAMP + 1000) / 1000,
+            type: 5,
+          },
+        ]);
+      });
+
+      it('correctly deny URL for xhr request', async () => {
+        options.networkDetailDenyUrls = [
+          'https://example.com/foo',
+          'com/bar',
+          /^http:\/\/example.com\/exact$/,
+          /^http:\/\/example.com\/partial/,
+        ];
+
+        const breadcrumb: Breadcrumb = {
+          category: 'xhr',
+          data: {
+            method: 'GET',
+            url,
+            status_code: 200,
+          },
+        };
+        const xhr = new XMLHttpRequest();
+        Object.defineProperty(xhr, 'response', {
+          value: 'test response',
+        });
+        Object.defineProperty(xhr, 'responseText', {
+          value: 'test response',
+        });
+        const hint: XhrBreadcrumbHint = {
+          xhr,
+          input: 'test input',
+          startTimestamp: BASE_TIMESTAMP + 1000,
+          endTimestamp: BASE_TIMESTAMP + 2000,
+        };
+        beforeAddNetworkBreadcrumb(options, breadcrumb, hint);
+
+        expect(breadcrumb).toEqual({
+          category: 'xhr',
+          data: {
+            method: 'GET',
+            request_body_size: 10,
+            response_body_size: 13,
+            status_code: 200,
+            url,
+          },
+        });
+
+        await waitForReplayEventBuffer();
+
+        expect((options.replay.eventBuffer as EventBufferArray).events).toEqual([
+          {
+            data: {
+              payload: {
+                data: {
+                  method: 'GET',
+                  request: {
+                    _meta: {
+                      warnings: ['URL_SKIPPED'],
+                    },
+                    headers: {},
+                    size: 10,
+                  },
+                  response: {
+                    _meta: {
+                      warnings: ['URL_SKIPPED'],
+                    },
+                    headers: {},
+                    size: 13,
+                  },
+                  statusCode: 200,
+                },
+                description: url,
+                endTimestamp: (BASE_TIMESTAMP + 2000) / 1000,
+                op: 'resource.xhr',
+                startTimestamp: (BASE_TIMESTAMP + 1000) / 1000,
+              },
+              tag: 'performanceSpan',
+            },
+            timestamp: (BASE_TIMESTAMP + 1000) / 1000,
+            type: 5,
+          },
+        ]);
+      });
+    });
   });
 });
diff --git a/packages/replay/test/utils/setupReplayContainer.ts b/packages/replay/test/utils/setupReplayContainer.ts
index 0237afddb538..e2a49052a799 100644
--- a/packages/replay/test/utils/setupReplayContainer.ts
+++ b/packages/replay/test/utils/setupReplayContainer.ts
@@ -12,6 +12,7 @@ const DEFAULT_OPTIONS = {
   useCompression: false,
   blockAllMedia: true,
   networkDetailAllowUrls: [],
+  networkDetailDenyUrls: [],
   networkCaptureBodies: true,
   networkRequestHeaders: [],
   networkResponseHeaders: [],