diff --git a/sycl/include/CL/__spirv/spirv_vars.hpp b/sycl/include/CL/__spirv/spirv_vars.hpp
index 53315cd9f72eb..bbc6f75ddf87b 100644
--- a/sycl/include/CL/__spirv/spirv_vars.hpp
+++ b/sycl/include/CL/__spirv/spirv_vars.hpp
@@ -15,7 +15,7 @@
 
 #define __SPIRV_VAR_QUALIFIERS extern "C" const
 
-#if defined(__SYCL_NVPTX__) || defined(__SYCL_EXPLICIT_SIMD__)
+#if defined(__SYCL_NVPTX__)
 
 SYCL_EXTERNAL size_t __spirv_GlobalInvocationId_x();
 SYCL_EXTERNAL size_t __spirv_GlobalInvocationId_y();