diff --git a/include/pybind11/typing.h b/include/pybind11/typing.h
index b7b1a4e54a..0ee329d85a 100644
--- a/include/pybind11/typing.h
+++ b/include/pybind11/typing.h
@@ -79,6 +79,13 @@ struct handle_type_name<typing::Tuple<>> {
     static constexpr auto name = const_name("tuple[()]");
 };
 
+template <typename T>
+struct handle_type_name<typing::Tuple<T, ellipsis>> {
+    // PEP 484 specifies this syntax for a variable-length tuple
+    static constexpr auto name
+        = const_name("tuple[") + make_caster<T>::name + const_name(", ...]");
+};
+
 template <typename K, typename V>
 struct handle_type_name<typing::Dict<K, V>> {
     static constexpr auto name = const_name("dict[") + make_caster<K>::name + const_name(", ")
diff --git a/tests/test_pytypes.cpp b/tests/test_pytypes.cpp
index 0cd480ebba..e840eb61f8 100644
--- a/tests/test_pytypes.cpp
+++ b/tests/test_pytypes.cpp
@@ -825,6 +825,8 @@ TEST_SUBMODULE(pytypes, m) {
 
     m.def("annotate_tuple_float_str", [](const py::typing::Tuple<py::float_, py::str> &) {});
     m.def("annotate_tuple_empty", [](const py::typing::Tuple<> &) {});
+    m.def("annotate_tuple_variable_length",
+          [](const py::typing::Tuple<py::float_, py::ellipsis> &) {});
     m.def("annotate_dict_str_int", [](const py::typing::Dict<py::str, int> &) {});
     m.def("annotate_list_int", [](const py::typing::List<int> &) {});
     m.def("annotate_set_str", [](const py::typing::Set<std::string> &) {});
diff --git a/tests/test_pytypes.py b/tests/test_pytypes.py
index 2b2027316c..cfb144523a 100644
--- a/tests/test_pytypes.py
+++ b/tests/test_pytypes.py
@@ -911,6 +911,13 @@ def test_tuple_empty_annotations(doc):
     )
 
 
+def test_tuple_variable_length_annotations(doc):
+    assert (
+        doc(m.annotate_tuple_variable_length)
+        == "annotate_tuple_variable_length(arg0: tuple[float, ...]) -> None"
+    )
+
+
 def test_dict_annotations(doc):
     assert (
         doc(m.annotate_dict_str_int)